Research

Peripheral Nerve

The Peripheral Nerve Research Group is part of the larger Neuroanesthesia Research Group in the Department of Anesthesiology at the University of California, San Diego School of Medicine. The Neuroanesthesia group consists of clinicians, researchers and students interested in mechanisms of inflammation and ischemia and who share space, resources, and common academic interests.

The Peripheral Nerve Research Group Is Involved In

  • Basic research studies of the peripheral nervous system
  • Defining the initial neural-immune mechanisms linking injury to the peripheral nervous system
  • Investigations relate directly to rationale for new therapy

the Group's Focus Is

  • Identifying mechanisms of neuronal damage
  • Elucidating role of MMPs in survival
  • Phenotypic remodeling of gila and neurons through proteolysis of extraceullular and cell surface factors
  • A dedicated NIH program centered on validating MMPs as early biomarkers of neuronal degeneration
  • Utlizling peripheral nerve injury as a model neuronal regeneration system for nerve repair
  • Research mechanisms of localized and central neuroinflammation leading to persisten nerve related injury

The Laboratory provides training for post-graduate scholars and for medical, graduate, and selected undergraduate students at UCSD. It also hosts the Editorial Office for the Journal of the Peripheral Nervous System, and the administrative offices of the Peripheral Nerve Society.

Peripheral Nerve Research Team

Investigators

Recent and current lab members

  • Senior Technician:
             Jennifer Dolkas
  • Postdoctoral trainees:

             Hideo Kobayashi, M.D., Ph.D.    
             Sharmila Chattopadhyay, Ph.D.        
             Kinshi Kato, M.D., Ph.D.
             Huaqing Liu, Ph.D.
             Maria Kim, M.D.

 

  • Undergraduate students:
             Elena Zininberg, UCSD, Molecular and Cellular biology
             Renata Ferreira, UCSD, Bioengineering